There are many forms of hormone replacement therapy available for those who seek remedies against the unpleasant symptoms of menopause. Different types of administration have their own set of advantages and disadvantages. Hormones can be taken orally as a tablet or spray, locally in the form of vaginal gel or tablet, and transdermally as well.
What is transdermal HRT?
Transdermal means the hormone supplement is applied on the skin in some way and it absorbs through it to reach the subcutaneous microcirculation, or the network of tiny veins under the skin. HRT can be used transdermally in the form of skin patches, gels, or sprays.
Benefits
Applying bioactive hormones through the skin resembles the natural way hormones are absorbed in the body. Transdermal application offers the lowest possible estrogen dosing for the shortest time, leaving time for the body to adjust. Transdermal application also bypasses the liver, completely freeing it from stress other orally taken medications may put it under.
Studies found that transdermal forms of HRT are worth considering because they have less adverse effects. This is due to the avoidance of liver metabolism and accumulation of metabolites with antiestrogenic activity. Data suggests that transdermal estrogen patches are both safer and potentially more effective than oral estrogen therapy.
Scientists also said that transdermal application has little or no effect on clotting factors, lipoproteins, sex hormone binding globulin, hepatic enzymes, or C-reactive protein. There is little to no increase in thromboembolic events, meaning a low risk of thrombosis or stroke with transdermal HRT. This is a very important factor if the patient is overweight, as it is one of the leading causes of the above-mentioned health issues. This administration method is also easy on blood pressure.
Compared to orally administered estrogen, a much lower dose of hormones is needed to combat the most notorious symptom of the perimenopausal period, hot flashes.
Consult your doctor
The precise composition of your personalized therapy against the symptoms of menopause is created by your doctor after thorough examination, screenings, tests, and a clear establishment of therapy goals. If you are affected as well, we recommend you consult your doctor about your options first.